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Just what is a virus?
Viruses
are complicated. Depending upon who you’re talking to,
they may be defined either as extremely simple microorganisms
or as extremely complex molecules. No matter which way you define
them however, there is no doubt that they are the causative
agents of various nasty infectious diseases. Each individual
viral particle consists of a protein coat (or capsid) surrounding
an RNA or DNA core of genetic material. This genetic material
provides the blueprints which allow the virus to reproduce itself
once it finds a host cell. The capsids may also be surrounded
by a fatty “envelope.” Viruses with an envelope
tend to disintegrate faster and not live as long outside the
host animal. Viruses (such as parvo) that are nonenveloped can
survive for much longer outside their host.
The
ultimate goal of every virus is to make as many copies of itself
as quickly as possible. In order to accomplish this, the viral
particles must enter a living cell. It accomplishes this by
using its capsid proteins to attach itself to the outside of
a cell. Once this has been accomplished, the viral particle
either injects its genetic material into the cell or enters
the cell whole, capsid and all. Either way, the virus uses the
cell’s built in machinery to replicate its own genetic
material over and over again. New virus particles escape the
confines of the cell either by “budding” out from
the cells surface a few at a time, or by crowding so many particles
inside the cell walls that the cell itself bursts and distributes
viral particles throughout its surroundings. In this manner
the virus infects more and more cells and spreads throughout
the body.
Some important definitions…
Below are some quick explanations of common scientific
terms
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Each
individual viral critter is referred to as a viral
particle. The term ‘particle’ is used
because it’s a bit of a stretch to call one an ‘organism’
due to their extremely small size and somewhat un-lifelike
characteristics. |
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The
nucleic acids (DNA or RNA) of each viral particle are surrounded
by a protein coat and sometimes a fatty envelope. This protein
coat and envelope are together referred to as the capsid.
The capsids are an extremely important element of the viral
particle, as their proteins determine to which cells the virus
can attach and infect. |
How
does a virus go about infecting an animal?
Put
simply, each viral particle needs to locate a host cell and
inject its nucleic acids inside the cell. This is where the
capsid proteins are important – they determine not only
what species the virus can infect (cat, dog, pig, human and
so forth) but also what cell type within the host it can infect.
Common viral targets include blood cells, intestinal cells,
and brain cells. Once the particle has bound to a specific cell,
it injects its DNA or RNA into the formerly healthy cell. Thinking
the new information is its own, the cell proceeds to make copy
upon copy of the virus until it either dies or explodes. Either
way, the virus uses the cell’s built in machinery to replicate
its own genetic material over and over again. New virus particles
escape the confines of the cell either by “budding”
out from the cells surface a few at a time, or by crowding so
many particles inside the cell walls that the cell itself bursts
and distributes viral particles throughout its surroundings.
In this manner the virus infects more and more cells and spreads
throughout the body.
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