Viruses:
West Nile Virus

West Nile Virus affects (but is not limited to) the following organs or anatomical structures:

- Brain
- Nervous System

An Overview of West Nile Virus

The West Nile Virus (WNV), a member of the flavivirus family, was first isolated during 1937 in the West Nile Region of Uganda. Despite having since caused encephalitis outbreaks in Africa, Eastern Europe, Western Asia, and the Middle East, WNV did not invade North America until its 1999 appearance in New York State. Infection with the virus can trigger a range of symptoms in humans, from none at all to mild, flu-like sensations to encephalitis, a potentially fatal inflammation of the brain.

WNV is a cause for concern partly because it has public health implications but largely because there is a great deal we do not yet know about it. We are not certain how the virus made its way to the United States. Speculation ranges from the illegal exotic bird trade to an errant mosquito catching a plane ride across the Atlantic. We don’t know why some people are more severely affected than others, though experts think it has to do with age and immune system efficacy. Precisely which animals are susceptible to the virus remains a bit of a mystery – the list of species with documented infections changes often.

The West Nile Virus is of concern to everyone – whether they own pets or not. But pet owners must take additional measures in order to limit the level of exposure for their pets. WNV is rapidly spreading to all corners of North America; 32 states and several Canadian provinces have already reported virus activity in 2003, compared to the mere 20 from last year. The following information is intended to provide you with an up-to-date overview of WNV, its dangers, and preventative measures you can take to minimize exposure for both you and your dog. It is important to remember however that specific information regarding veterinary insect repellents and the like should always be gained from your veterinarian.

How does infection occur?

WNV is harbored by mosquitoes of many kinds – at least 20 species are known to be carriers. A mosquito contracts the virus upon biting an infected animal, most often a bird. The infected mosquito then transmits the virus to new animals when it finds and bites a suitable host. It should be remembered that relatively few mosquitoes carry the virus and that even if an animal is bitten by an infected mosquito it will not necessarily become infected.

It is also possible for WNV to be transmitted via blood transfusions and organ transplants, but this has only occurred in a very few cases and should not be viewed as a serious threat. It is not believed that WNV can be transmitted through casual touching or kissing. Further, there is no evidence that an infected dog, cat or other animal can pass the virus directly to humans, so this should not be of concern to owners of infected pets.

What are the symptoms of WNV?

In humans there is an incubation period of 3 to 14 days between initial infection and onset of symptoms. The incubation period in dogs is much longer and may last up to several months.

Approximately 80% of infected humans – and likely just as many or more dogs – never suffer any visible symptoms of WNV. Of those people that do develop symptoms, the great majority suffer only mild effects. Mild cases present like the common flu, with fever, headache, nausea, vomiting, and sometimes swollen lymph nodes and a rash on the chest, stomach and back. Vague symptoms usually endure for only a few days and are not fatal.

More severe human cases, which strike a mere 1 in 150 infected but may well prove fatal, are indicated by high fever, headache, neck stiffness, stupor, disorientation, coma, tremors, convulsions, muscle weakness, vision loss, numbness, and paralysis. These more sever symptoms, if they do not prove fatal, may last several weeks, and neurological damage is often permanent.

Dogs seem to be more resistant to the virus than humans and rarely fall ill, but certain symptoms have been observed consistently across cases. Signs of a WNV infection in your dog may include poor coordination, depression, decreased appetite, difficulty walking, tremors, abnormal head posture, circling, and convulsions. Such symptoms may be indicative of a number of disorders, but all are serious and any dog exhibiting neurological abnormalities should be promptly examined by a veterinarian.

Diagnosis of WNV is finalized using laboratory tests which must be administered by a medical professional or veterinarian.

What are the treatment options for animals with WNV?

Treatment is almost purely supportive and symptom-specific. At this point nearly every dog infected with WNV is expected to recover fully.

Is there a vaccine available for WNV?

Unfortunately, no. There is a vaccine on the market for use on horses, but none exists at this time for humans or small animals.

How else can I help prevent the disease?

Given that much about WNV remains a mystery, our best defense is currently prevention. A number of steps may be taken to reduce risk for both you and your pets.

Limiting exposure to mosquitoes is perhaps the most obvious but also the most effective method of prevention. Mosquitoes tend to be at their most active early in the morning and near dusk. Keeping yourself and your pet indoors as much as possible during these hours will expose you to fewer insects.

It is important to ensure that all window and door screens are in good repair. This will minimize the number of mosquitoes that can enter your home.

When you do venture outdoors, insect repellents can minimize the number of times an individual is bitten. For humans, repellents containing DEET are the most effective. Because DEET can be harmful if ingested, it is no approved or appropriate for use on animals – while grooming they could easily ingest the spray or residue. There are however a number of products approved for use on dogs. Some of them are marketed as equine products, but they are safe for canine companions as well.

  • Flysect Super 7 by Equicare
  • Petguard gel by Virbac
  • VIP Fly Repellent Ointment by VPL
  • Flea and Tick Mist by Davis
  • Adams Flea and Tick Mist by VPL
  • Happy Jack Flea-Tick Spray by Happy Jack
  • Ultrashield by Absorbine

These products are available at local pet and feed stores or through your veterinarian.

Additional resources on the web:

Centers for Disease Control
In-depth West Nile site contains question and answer sections, data on current case count, prevention techniques, and more.

VetCentric
Summarizes what is known about West Nile, how to protect domestic animals (including dogs and horses) and links to webpages with other information.

VeterinaryPartner.com
Discusses West Nile in a Question & Answer format focused on dogs and cats.



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Section Updated 9 May 2004 (Created 20 Aug 2003)

Copyright © 2004. James A. Baker Institute for Animal Health.
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Disclaimer: The information on this website is intended for educational purposes only and does
not replace the medical advice and treatment received from your veterinarian or pet care provider.