Baker Institute Research Discoveries and Achievements
| 1951 | Discovery of carrier state in canine hepatitis infections. |
| 1952 | First vaccine for infectious canine hepatitis. |
| 1955 | Recognition of role of Mycoplasma in kennel cough. |
| 1956 | First combined vaccines for dogs. |
| 1958 |
Standardization of canine distemper virus serum neutralization tests. |
| 1960 | Development of national distemper immunization program. |
| 1965 | Discovery and isolation of canine herpesvirus. |
| 1966 | Isolation and characterization of Brucella canis. |
| 1970 | Definition of the pathogenesis of canine distemper. |
| 1974 | First practical test for diagnosis of canine brucellosis. |
| 1977 | Description of pathogenesis of Bordetella bronchiseptica infection in dogs. |
| 1978 | Isolation of canine parvovirus-type 2 (CPV-2). |
| 1979 | First vaccines for CPV-2. |
| 1981 | Perfection of attenuated vaccine for CPV-2; Discovery of a metabolic defect linked to osteoarthritis in dogs. |
| 1982 | First report of greatly increased fibronectin in early-osteoarthritic cartilage of dogs. |
| 1984 | First successful transplantation of horse embryos into mules. |
| 1985 | Discovery of CPV-2a. |
| 1987 | Development of monoclonal antibodies to equine influenza virus. |
| 1989 | Genetic mapping of the mutation that enabled canine parvovirus (CPV) to infect dogs. |
| 1990 | Solution of atomic structure of CPV. |
| 1991 | Solution of atomic structure of feline panleukopenia virus; Discovery of CPV-2b. |
| 1992 | First identification of a candidate gene for an inherited eye disease of dogs, rod-cone dysplasia 1. |
| 1993 | First cloning of horse gamma interferon. |
| 1994 | First DNA blood test for an inherited eye disease of dogs, rcd-1; Cloning and expression of canine erythropoietin (EPO). |
| 1996 | Demonstration that articular cartilage contains a unique isoform of fibronectin; Successful clinical trial of recombinant canine EPO therapy. |
| 1997 | Development of an accurate, early diagnostic test for canine hip dysplasia; Identification of interleukin-8 as an initiator of arthritis in dogs with Lyme disease; First publication of a linkage map of the canine genome. |
| 1998 | Successful in vitro gene therapy to correct disease in retinal cells; Identification of the mutation causing MPS VII in dogs. MPS VII is an inherited lysosomal storage disorder leading to diseases in multiple organs. Linkage mapping of the locus for progressive rod-cone degeneration in dogs; Development of first practical diagnostic tests for the minute virus of canines. |
| 2002 | First gene therapy to restore sight in congenitally blind dog. |
| 2003 | Cooperative international study of genetics of immunity in horses exploring the nature of disease and how to control its spread. |
| 2004 | Development of molecular markers for gene mapping in the silver fox. |
| 2005 | Production of monoclonal antibodies for identifying immunoglobulins of llamas and alpacas. |
| 2005 | First application of gene chip technology to studies of canine osteoarthritis. |
| 2006 | Baker Institute research mare "Twilight" selected as the donor horse for the equine whole genome sequencing project. |
| 2006 | Mapping of canine rod cone dysplasia type 2 (rcd2) to a region of dog chromosome 7. |
| 2006 | Demonstration that virulent systemic feline calicivirus isolates appear to arise sporadically from the general pool of feline caliciviruses. |